Its earliest titles were Mangazine and Extremely Silly Comics.
Many now-established names have started at Antarctic, with most continuing to work there, including Brian Denham, Ben Dunn, Eisner-nominated Rod Espinosa, Guru eFX, Joseph Wight, and Chris Bunting. Graphic novelist Alex Robinson serializes his first book, Box Office Poison, with Antarctic in the 1990s.
The company also produces a wide range of "how-to" and "you can" comics, instructing on many areas of comic book creation and craft.
Many of Antarctic's staple characters from titles including Warrior Nun Areala, Ninja High School, Gold Digger, The Courageous Princess, and Dragons Arms, came together in the 2005 How to Break into Comics, which also featured their creators in the narrative.
In April 2006, popular title Warrior Nun was re-launched as Warrior Nun Lazarus and included CGI coloring.
In the 1990s, the company also published numerous furry comic books such as a revived Albedo Anthropomorphics. In 1998, some of these titles moved off to a separate company, Radio Comix.